Sam Garg Image

Sep 19, 2024 | Healthcare Everything

Dr. Sumit Garg: Innovating Eye Care for a Brighter Tomorrow

Sumit (Sam) Garg, MD, reflects on his influential journey in ophthalmology, highlighting groundbreaking innovations and research at the Gavin Herbert Eye Institute, while showcasing promising advancements in corneal and refractive surgery that are shaping the future of the field.

Headshot of Sumit Garg

Sep 06, 2024 | Ophthalmology Times Europe

Magnetic cell therapy for corneal endothelial dysfunction

At the American Society of Cataract and Refractive Surgery annual meeting in Boston, Sumit Garg, MD, presented promising data from a phase 1 multicenter study indicating that magnetic cell delivery of human corneal endothelial cells (HCECs) to the anterior chamber is emerging as a safe and innovative cell-based treatment. The approach is showing early signs of efficacy in addressing corneal endothelial cell dysfunction, offering a potential breakthrough in treating conditions like Fuchs dystrophy and pseudophakic bullous keratopathy.
Stephan Prepas, MD Headshot

Aug 08, 2024 | KNBC

Olympians with glasses inspiring athletes with imperfect vision

Stephen Prepas, MD Pediatric ophthalmologist at UCI Health and the UCI Gavin Herbert Eye Institute, talks about Olympic gymnast Stephen Nedoroscik and the eye issues he deals with
headshot of Marjan Farid, MD

Jul 10, 2024 | Ophthalmology Times

Marjan Farid, MD, recognized for eye care innovations

Marjan Farid, MD, received the Roger Steinert, MD, Legacy Award at the Octane Ophthalmology Tech Forum, held June 20-21 at the Newport Beach Marriott Hotel & Spa in Irvine, California.
Sam Garg

Jun 24, 2024 | Ophthalmology Times

Magnetic cell therapy is a potential treatment option for corneal endothelial dysfunction

Magnetic cell delivery of human corneal endothelial cells (HCECs) to the anterior chamber seems to be a safe cell-based treatment that is exhibiting early signs of efficacy for corneal endothelial cell dysfunction, Sumit Garg, MD, ABO, reported at the American Society of Cataract and Refractive Surgery 2024 annual meeting in Boston, Massachusetts.
Marjan Farid Live Well Photo

Mar 18, 2024 | ASCRS EyeWorld

Treatment of limbal stem cell deficiency

Identifying and treating patients with limbal stem cell dysfunction or deficiency can be a challenging process. Several physicians discussed how they handle these patients, including which techniques are available for mild to more severe disease.
Marjan Farid Image

Oct 10, 2023 | Review of Ophthalmology

What to do with a White Cataract

The challenges to expect and tips for successful management of these complicated cases.
Graphical Abstract RGR Image

Aug 29, 2023 | Cell Reports Journal

Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia

In daylight, demand for visual chromophore (11-cis-retinal) exceeds supply by the classical visual cycle. This shortfall is compensated, in part, by the retinal G-protein-coupled receptor (RGR) photoisomerase, which is expressed in both the retinal pigment epithelium (RPE) and in Müller cells. The relative contributions of these two cellular pools of RGR to the maintenance of photoreceptor light responses are not known. Here, we use a cell-specific gene reactivation approach to elucidate the kinetics of RGR-mediated recovery of photoreceptor responses following light exposure. Electroretinographic measurements in mice with RGR expression limited to either cell type reveal that the RPE and a specialized subset of Müller glia contribute both to scotopic and photopic function. We demonstrate that 11-cis-retinal formed through photoisomerization is rapidly hydrolyzed, consistent with its role in a rapid visual pigment regeneration process. Our study shows that RGR provides a pan-retinal sink for all-trans-retinal released under sustained light conditions and supports rapid chromophore regeneration through the photic visual cycle.
Dr Farid in Clinic Image

Apr 25, 2023 | Forbes Health

Red Eyes (Bloodshot Eyes): Causes And Treatment

Red eyes, also called bloodshot eyes, can be caused by various factors and are a common issue most people experience at some point. It’s important to understand the possible reasons behind red eyes because while some underlying causes are harmless, others can indicate a medical concern, be contagious and/or require medical attention.
Schematic representation of precision genome editing in treating inherited retinal diseases.

Oct 13, 2022 | Ophthalmology Times

UCI-led report illustrates potential of precision genome editing in treating inherited retinal diseases

According to UCI researchers, current preclinical successes and clinical genome editing approaches for treating inherited retinal degenerative disease and stresses there is hope that in vivo gene editing will be the future treatment paradigm for these diseases.