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Mar 18, 2024 | ASCRS EyeWorld
Treatment of limbal stem cell deficiency
Identifying and treating patients with limbal stem cell dysfunction or deficiency can be a challenging process. Several physicians discussed how they handle these patients, including which techniques are available for mild to more severe disease.
Oct 10, 2023 | Review of Ophthalmology
What to do with a White Cataract
The challenges to expect and tips for successful management of these complicated cases.
Aug 29, 2023 | Cell Reports Journal
Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia
In daylight, demand for visual chromophore (11-cis-retinal) exceeds supply by the classical visual cycle. This shortfall is compensated, in part, by the retinal G-protein-coupled receptor (RGR) photoisomerase, which is expressed in both the retinal pigment epithelium (RPE) and in Müller cells. The relative contributions of these two cellular pools of RGR to the maintenance of photoreceptor light responses are not known. Here, we use a cell-specific gene reactivation approach to elucidate the kinetics of RGR-mediated recovery of photoreceptor responses following light exposure. Electroretinographic measurements in mice with RGR expression limited to either cell type reveal that the RPE and a specialized subset of Müller glia contribute both to scotopic and photopic function. We demonstrate that 11-cis-retinal formed through photoisomerization is rapidly hydrolyzed, consistent with its role in a rapid visual pigment regeneration process. Our study shows that RGR provides a pan-retinal sink for all-trans-retinal released under sustained light conditions and supports rapid chromophore regeneration through the photic visual cycle.
Apr 25, 2023 | Forbes Health
Red Eyes (Bloodshot Eyes): Causes And Treatment
Red eyes, also called bloodshot eyes, can be caused by various factors and are a common issue most people experience at some point. It’s important to understand the possible reasons behind red eyes because while some underlying causes are harmless, others can indicate a medical concern, be contagious and/or require medical attention.
Oct 13, 2022 | Ophthalmology Times
UCI-led report illustrates potential of precision genome editing in treating inherited retinal diseases
According to UCI researchers, current preclinical successes and clinical genome editing approaches for treating inherited retinal degenerative disease and stresses there is hope that in vivo gene editing will be the future treatment paradigm for these diseases.
Oct 01, 2022 | Ophthalmology Times
Expanding accessibility of vision correction with spectacles for children with cranial abnormalities
Donny Suh MD, Chief of Pediatric Ophthalmology and Strabismus at UCI's Gavin Herbert Eye Institute in Irvine CA, discusses special glasses he invented. The Omni glasses are designed for children with any forms of cranial dystosis. The glasses are adjustable to any head size and are printed on a 3D printer.
Sep 27, 2022 | CIsion PRWeb
NCCVEH Names Dr. Donny W. Suh, Gavin Herbert Eye Institute, UC Irvine, as Recipient of the 8th Annual Bonnie Strickland Champion for Children’s Vision Award
Donny W. Suh, MD, FAAP, MBA, FACS, Chief of Pediatric Ophthalmology and Strabismus, and Professor, Department of Ophthalmology and Visual Science, Gavin Herbert Eye Institute, University of California, Irvine, named recipient of the 8th Annual Bonnie Strickland Champion for Children’s Vision Award from the National Center for Children's Vision and Eye Health at Prevent Blindness
Aug 19, 2022
Krzysztof Palczewski, PhD, wins 2022 Ludwig von Sallmann prize
Krzysztof Palczewski, PhD, has been named the recipient of the 2022 Ludwig von Sallman Prize, a prestigious award is given every two years to an individual who has distinguished themselves by making a significant contribution to vision research and ophthalmology.
Apr 23, 2022 | The American Society of Cataract and Refractive Surgery
Roger Steinert, MD elected to ASCRS Ophthalmology Hall of Fame
The late Roger Steinert, MD, past Chair of the Department of Ophthalmology at the Gavin Herbert Eye Institute was inducted into the American Society of Cataract and Refractive Surgery (ASCRS) ophthalmology Hall of Fame.
Apr 07, 2022 | IEEE Spectrum
Andrew Browne, MD, PhD on color night vision enhanced by AI.
In a new study, with the help of deep-learning AI technology, scientists have devised a way in which infrared vision might help see the visible colors in a scene in the absence of light.